Find out how we help our people perform at their best. The subgroup analysis from the PROfound Phase III trial showed Lynparza reduced the risk of disease progression or death by 78% (based on a hazard ratio [HR] of 0.22, 95% confidence interval [CI], 0.15-0.32; nominal p<0.0001) and improved rPFS to a median of 9.8 months versus 3.0 with enzalutamide or abiraterone in men with mCRPC with BRCA1/2 mutations. Click ‘cancel’ to return to AstraZeneca’s site or ‘continue’ to proceed. Our country sites can be located in the AZ Network. AstraZeneca (LSE/STO/Nasdaq: AZN) is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three therapy areas - Oncology, Cardiovascular, Renal & Metabolism, and Respiratory & Immunology. Employment. Lynparza is being tested in a range of PARP-dependent tumour types with defects and dependencies in the DDR pathway. Adverse events should also be reported to AstraZeneca on 0800 783 0033 or via https://aereporting.astrazeneca.com Visit site VVPM ID: GB-21240 Date of Prep: April 2020 AstraZeneca provides this link as a service to website visitors. the world by delivering life-changing medicines as one Source: Annual Report 2010, p. 44 INTERNATIONAL AstraZeneca (Global HQ) Floors 7-9, Two Kingdom Street, Paddington Central London, W2 6BD United … Our support for the COVID-19 response in the UK, Visit the COVID-19 Global information hub, Working with government and policy makers, Medical and Educational Goods and Services, AZ Medical and Educational Goods and Services in Diabetes, AZ Medical and Educational Goods and Services in Asthma.
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AstraZeneca will use your information to send you answers to queries, for administration purposes and for statisitical analysis. This website is intended for people seeking information on AstraZeneca's UK business. Lynparza now provides a targeted treatment option at a molecular level to patients with advanced prostate cancer who have historically poor prognosis and few treatment options.”, Dave Fredrickson, Executive Vice President, Oncology Business Unit, said: “Lynparza more than tripled radiographic progression-free survival and is the only PARP inhibitor to show an overall survival benefit versus certain new hormonal agents for men with BRCA-mutated metastatic castration-resistant prostate cancer.
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